Thymosin Alpha-1
Not ApprovedStrong EvidenceThymalfasin
A thymic peptide that modulates innate and adaptive immunity — FDA-approved in 35+ countries for hepatitis and cancer immunotherapy.
Half-Life
~2 hours
Molecular Weight
3108.4 g/mol
Thymosin Alpha-1 (Tα1) is a 28-amino-acid peptide naturally secreted by the thymus gland that plays a central role in T-cell maturation and immune modulation. It is FDA-approved in over 35 countries (as Zadaxin) for the treatment of hepatitis B, hepatitis C, and as an adjunct to cancer immunotherapy and vaccines. In the US, it remains an investigational compound. Tα1 has been studied extensively for its ability to enhance T-cell function and innate immunity without overstimulating inflammatory pathways — an unusual immunomodulatory profile with therapeutic potential in chronic infections, cancer, and vaccine enhancement.
Also Known As
Amino Acid Sequence
Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH
Reconstitution
Reconstitute with sterile water for injection. Typical concentration: 1.6 mg/mL (standard clinical vial).
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