CJC-1295

Research OnlyModerate Evidence

CJC-1295 (Without DAC)

A modified GHRH analog with extended half-life, commonly stacked with Ipamorelin for synergistic GH pulse amplification.

Half-Life

~30 minutes

Molecular Weight

3367.9 g/mol

CJC-1295 without DAC (also called Modified GRF 1-29) is a modified version of sermorelin with four amino acid substitutions that extend its half-life from ~10 minutes to ~30 minutes while preserving GHRH receptor affinity. It is almost exclusively used in combination with a GHRP such as Ipamorelin, as the two work synergistically — CJC-1295 amplifies the GH pulse while Ipamorelin triggers its release. This combination is considered one of the most physiologically sound GH optimization protocols in research medicine.

Also Known As

Modified GRF 1-29Mod GRF 1-29CJC-1295 no DAC

Amino Acid Sequence

Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2

Reconstitution

Reconstitute with bacteriostatic water. Typical concentration: 1 mg/mL.

Open Reconstitution Calculator →

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