AOD-9604
Research OnlyModerate EvidenceAnti-Obesity Drug 9604
A modified fragment of human growth hormone studied for fat metabolism and cartilage regeneration without GH's systemic effects.
Half-Life
~30 minutes
Molecular Weight
1817.1 g/mol
AOD-9604 is a modified fragment of human growth hormone (hGH) corresponding to amino acids 177–191 of the C-terminal region. It was specifically engineered to retain hGH's fat-burning properties while eliminating its growth-promoting and insulin-desensitizing effects. AOD-9604 reached Phase II/III clinical trials for obesity treatment, demonstrating a favorable safety profile though modest efficacy as a standalone anti-obesity drug. More recent research has investigated its potential in cartilage and bone repair, with a Phase II trial completed in osteoarthritis.
Also Known As
Amino Acid Sequence
Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe-NH2
Reconstitution
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